May 27, 2024

Oligonucleotide Synthesis Market Propelled by DNA-based Therapeutics for Genetic Diseases

Oligonucleotide Synthesis Market Overview: The Oligonucleotide Synthesis Market involves production of small nucleic acid polymers such as DNA and RNA using solid-phase chemistry techniques. These short DNA and RNA sequences finds applications in drug discovery, genetic testing and DNA-based therapeutics.

The global Oligonucleotide Synthesis Market is estimated to be valued at US$ 4565 Bn in 2024 and is expected to exhibit a CAGR of 13% over the forecast period 2024 to 2031, as highlighted in a new report published by Coherent Market Insights.

Market key trends:

DNA-based therapeutics such as antisense oligonucleotides, DNA vaccines, and gene silencing have shown great potential in the treatment of inherited disorders like Tay-Sachs disease, sickle cell anemia, thalassemia, and different types of cancers that have genetic roots. Oligonucleotides are short DNA or RNA molecules that bind to mRNAtargets through the cellular mechanism of antisense inhibition or RNA interference to block gene expression. Their growing applications in developingtargeted therapies for previously untreatable medical conditions is expected to boost the demand for oligonucleotide synthesis over the forecast period.

SWOT Analysis
Strength: High demand for oligonucleotides in biomedical research and therapeutic applications. Advancements in synthesis technologies have improved oligonucleotide quality and yield.
Weakness: High costs associated with oligonucleotide synthesis and requirements for specialized equipment and skills. Challenges in scale-up and commercial production.
Opportunity: Growing investments in fields like genomics and precision medicine. Increasing global R&D spending on specialty applications like CRISPR genome editing.
Threats: Stringent regulations associated with clinical-grade oligonucleotides. Competition from alternative technologies in few niche applications.

Key Takeaways
The global oligonucleotide synthesis market is expected to witness high growth.

Regional analysis: The North America region currently dominates the oligonucleotide synthesis market owing to presence of major industry players and ongoing clinical trials. The oligonucleotide synthesis market in Asia Pacific is expected to exhibit fastest growth over the forecast period supported by increasing investments in bioscience R&D by China and India.

Key players operating in the oligonucleotide synthesis market are Forte Research Systems, ICON, Bio-Optronics, DSG, ArisGlobal, ERT Clinical, Oracle, Medidata Solutions, and MedNet Solutions among others. These players are focusing on new product launches, collaborations and expansion strategies to strengthen their market position.

1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it